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In general, compression works best on tables that include a reasonable number of character string columns and where the data is read far more often than it is written. Because there are no guaranteed ways to predict whether or not compression benefits a particular situation, always test with a specific workload and data set running on a representative configuration. Consider the following factors when deciding which tables to compress.
This is the User’s Guide for InnoDB storage engine 1.1 for MySQL 5.5, generated on 2010-04-13 (revision: 19994) .