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With the InnoDB storage engine it now is possible to chance certain system configuration parameters dynamically, without shutting down and restarting the server as was previously necessary. This increases up-time and facilitates testing of various options. You can now set these parameters dynamically:
This is the User’s Guide for InnoDB storage engine 1.1 for MySQL 5.5, generated on 2010-04-13 (revision: 19994) .